Female Founders Pioneering the Next Wave of B2B Solutions

Across industries as diverse as cybersecurity, legal tech, sustainability, and AI governance, women leaders are reshaping how businesses work with each other—and raising the bar for B2B innovation.

The business-to-business (B2B) startup space is a dynamic and often underappreciated arena of innovation. While consumer-facing platforms frequently steal the spotlight, B2B startups quietly transform industries by building tools, systems, and services that power how enterprises operate. From AI-driven sustainability platforms to legal software, these ventures are shaping the backbone of global commerce. Increasingly, female founders are leading the charge—introducing solutions that combine deep technical expertise with a strong understanding of market gaps.

Here are some of the remarkable women behind the most exciting B2B companies today.

Anastasia Kuskova — Sirius

Based in Amsterdam, Anastasia Kuskova is the cofounder and CEO of Sirius, an AI sustainability intelligence startup serving the mining, metals, and energy value chains. At a time when ESG compliance is no longer optional, Sirius equips resource-intensive industries with data tools to monitor environmental impact, track carbon performance, and meet regulatory standards. Kuskova’s vision is enabling heavy industries to move toward greener, more accountable futures.

Brittany Greenfield — Wabbi

In Boston, Brittany Greenfield is building a bridge between cybersecurity and enterprise development through Wabbi. As founder and CEO, she’s tackling the complex challenge of embedding security directly into software development cycles. Wabbi provides scalable application security that helps enterprises move fast without compromising safety—an urgent need in today’s digital-first economy.

Emma Rees — Deployed

Emma Rees, cofounder of Deployed, recognized a recurring issue in enterprise project management: poorly defined statements of work. Her collaborative platform is designed to inject clarity, efficiency, and alignment into SOW creation. By turning what was once a vague and frustrating process into a transparent workflow, Rees helps enterprises reduce risks and wasted resources.

Jacqueline Schafer — Clearbrief

Seattle-based Jacqueline Schafer, founder and CEO of Clearbrief, is transforming legal writing. Her platform enables litigators to see how each sentence is backed by evidence, improving accuracy and credibility in briefs. Clearbrief not only enhances efficiency for lawyers but also raises the standard of rigor in the legal profession—a powerful example of B2B technology improving professional outcomes.

Joanathan McIntosh — Opaper

From Jakarta, Joanathan McIntosh leads Opaper, a B2B commerce technology company that simplifies how businesses manage online and social media sales. With Southeast Asia’s booming digital economy, Opaper helps merchants integrate fragmented sales channels into a single streamlined system, empowering small and mid-sized enterprises to grow.

Liyana (Li) Sulaiman — Pollen

In Singapore, Liyana (Li) Sulaiman cofounded Pollen alongside Melanie (Holohan) Vernoia. Serving as chief product and technology officer, Sulaiman focuses on sustainable liquidation solutions. Pollen helps brands automate B2B sales of overstock and near-expiry goods, turning potential waste into opportunity. In doing so, Sulaiman’s work intersects sustainability and profitability—two forces reshaping retail supply chains.

Nicole Sahin — Globalization Partners

Nicole Sahin, founder and CEO of Globalization Partners, is a trailblazer in global workforce solutions. Her SaaS platform enables companies to hire, onboard, and manage employees across borders while remaining compliant with local regulations. By removing barriers to global hiring, Sahin’s company has empowered organizations to scale internationally with unprecedented ease.

Prukalpa Sankar — Altan

Serial entrepreneur Prukalpa Sankar is behind Singapore’s Altan, an AI governance platform ensuring companies prepare their data for AI adoption responsibly. With regulations tightening and AI expanding rapidly, Sankar’s vision ensures businesses don’t just use AI—they use it ethically and effectively. She brings both technical acumen and an eye for responsible innovation.

Purvanshi Mehta — Lica World

In San Francisco, Purvanshi Mehta cofounded Lica World, an AI-driven video producer that helps customer success, product, and sales teams generate professional-grade content quickly. By automating video creation, Mehta’s platform enables businesses to communicate complex ideas with speed and polish—an advantage in today’s fast-moving digital landscape.

A Broader Movement

What unites these founders is not only their gender but their approach to solving some of business’s most pressing problems. They are working across borders—Amsterdam, Boston, Singapore, Jakarta, and San Francisco—and across sectors as varied as legal services, e-commerce, cybersecurity, and sustainability. Each is rethinking inefficiencies in how businesses operate, offering digital-first solutions that scale globally.

For years, female founders have been underrepresented in venture capital and B2B technology. Yet the rise of these leaders suggests momentum is shifting. Their companies don’t just represent successful startups; they embody a broader movement toward inclusive, impact-driven entrepreneurship.

As global enterprises increasingly rely on B2B solutions for everything from compliance to collaboration, the contributions of these women are helping shape the infrastructure of tomorrow’s economy. They are building tools that allow businesses to grow more securely, sustainably, and intelligently—a quiet but profound revolution in how the world works.